1095037-75-4Relevant academic research and scientific papers
Synthesis of β-lactam peptidomimetics through Ugi MCR: First application of chiral Nβ-Fmoc amino alkyl isonitriles in MCRs
Vishwanatha,Narendra,Sureshbabu, Vommina V.
, p. 5620 - 5624 (2011/11/06)
Chiral Nβ-Fmoc amino alkyl isonitriles were employed in Ugi multi component reactions (Ugi 4C-3CR) to obtain functionalized β-lactam peptidomimetics with l-aspartic acid α-methyl ester/peptide ester and organic aldehydes. The reactions were carried out in MeOH. Thirteen Ugi products have been prepared in good to moderate yields with good diastereoselectivities.
Chiral N-Fmoc-β-amino alkyl isonitriles derived from amino acids: First synthesis and application in 1-substituted tetrazole synthesis
Sureshbabu, Vommina V.,Narendra,Nagendra
supporting information; experimental part, p. 153 - 157 (2009/04/07)
(Chemical Equation Presented) A novel class of optically active N-Fmoc-protected amino isonitriles has been described for the first time. Conversion of the carboxyl group of Fmoc-β-amino acids into an isocyano group has resulted in a new class of N-uretha
