1095141-87-9Relevant academic research and scientific papers
The synthesis of cyclopenta[c]pyridine (2-Pyrindene) derivatives
Dotsenko, Victor V.,Krivokolysko, Sergey G.,Litvinov, Victor P.
, p. 271 - 275 (2008)
Ethyl 2-(N-morpholinyl)cyclopent-1-ene-1-carboxylate reacted smoothly with cyanothioacetamide to give morpholinium 4-cyano-1-oxo-2,5,6,7-tetrahydro-1H- cyclopenta[c]pyridine-3-thiolate; the former when treated with N-benzyl-α-chloroacetamide gave either a S-alkyl derivative or cyclopenta[d]thieno[2,3-b]pyridine, depending on the reaction conditions. Under Mannich-type aminomethylation with primary amines and formaldehyde the above thiolate afforded derivatives of the previously unknown heterocyclic system, cyclopenta[g]pyrido[2,1-b][1,3,5]thiadiazine in 81-90% yields.
