1095278-62-8Relevant articles and documents
Asymmetric 1,3-dipolar cycloaddition with a P-stereogenic dipolarophile: An efficient approach to novel P-stereogenic 1,2-diphosphine systems
Vinokurov, Nikolai,Pietrusiewicz, K. Michal,Frynas, Slawomir,Wiebcke, Michael,Butenschoen, Holger
supporting information; experimental part, p. 5408 - 5410 (2009/03/11)
The asymmetric 1,3-dipolar cycloaddition of the P-stereogenic dipolarophile (SP,SP)-6 to C,N-diphenylnitrone (7) led to previously unknown P-stereogenic isoxazolinyl diphosphine dioxides (RP,S P)-8 in enantio- and diastereomerically pure form; their stereospecific reduction with Ti(OiPr)4/PMHS proceeds in high yield with retention of configuration at the phosphorus atoms to give enantio- and diastereomerically pure diphosphines, which are conveniently purified via the corresponding diphosphine-diboranes. The Royal Society of Chemistry.