1095280-71-9

Basic information

• Product Name: N-Boc-N-(3-trifluoromethylphenyl)hydroxylamine
• Synonyms: N-Boc-N-(3-trifluoromethylphenyl)hydroxylamine
• CAS NO: 1095280-71-9
• Molecular Weight: 277.243
• Mol File: 1095280-71-9.mol

Chemical Properties

• CAS DataBase Reference: N-Boc-N-(3-trifluoromethylphenyl)hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-N-(3-trifluoromethylphenyl)hydroxylamine(1095280-71-9)
• EPA Substance Registry System: N-Boc-N-(3-trifluoromethylphenyl)hydroxylamine(1095280-71-9)

Safety Data

• Hazardous Substances Data: 1095280-71-9(Hazardous Substances Data)

Upstream product

• 98-46-4 3-trifluoromethylnitrobenzene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 38160-76-8 N-<3-(α,α,α-Trifluoromethyl)phenyl>hydroxylamine 

Downstream Products

• 1095280-75-3 N-Boc-N-(3-trifluoromethylphenyl)-O-(4-nitrobenzoyl)hydroxylamine 
• 1095280-85-5 2-(Boc-amino)-4-trifluoromethylphenyl methanesulfonate 
• 1095280-86-6 2-(Boc-amino)-6-trifluoromethylphenyl methanesulfonate 

Relevant articles and documents

Regioselective installation of fluorosulfate (-OSO2F) functionality into aromatic C(sp2)-H bonds for the construction of: Para-amino-arylfluorosulfates

The construction of para-amino-arylfluorosulfates was achieved through installation of fluorosulfate (-OSO2F) functionality into aromatic C(sp2)-H bonds by the reaction of N-arylhydroxylamine with sulfuryl fluoride (SO2Fs

Rearrangement of differentially protected N-arylhydroxylamines

The rearrangement of a series of N,O-difunctionalised N-arylhydroxylamines to generate protected 2-aminophenols has been investigated. N-Boc-N-Aryl-O- acylhydroxylamines are stable, isolable compounds which rearrange smoothly at temperatures between 110 and 140°C. The corresponding N-Boc-N-aryl-O- sulfonylhydroxylamines were not isolated and rearrange to 1,2-difunctionalised aminophenols at room temperature in excellent yield. Deprotection of either the N- or O-substituents under standard conditions allows for further synthetic manipulation of either the aniline or phenol functionality. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.