Leucinostatin K is a cyclic hexapeptide that originates from the marine bacterium Paenibacillus larvae. It is recognized for its notable antibacterial and antifungal properties, which are attributed to its ability to disrupt the cell membrane of target organisms, ultimately leading to their demise. Furthermore, leucinostatin K has demonstrated potential as an anticancer agent, with research indicating its capacity to induce apoptosis in cancer cells. leucinostatin K's inhibitory effects on certain enzymes also suggest its potential in the development of novel therapeutic agents. Leucinostatin K's diverse biological activities and potential applications in medicine and agriculture have garnered significant interest.
109539-57-3
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Basic information
- Product Name: leucinostatin K
- Synonyms: leucinostatin K
- CAS NO:109539-57-3
- Molecular Formula: C62H111 N11 O14
- Molecular Weight: 1234.63
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 1444.6°C at 760 mmHg
- Flash Point: 827.4°C
- Appearance: /
- Density: 1.128g/cm3
- Vapor Pressure: 0mmHg at 25°C
- Refractive Index: 1.517
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: leucinostatin K(CAS DataBase Reference)
- NIST Chemistry Reference: leucinostatin K(109539-57-3)
- EPA Substance Registry System: leucinostatin K(109539-57-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 109539-57-3(Hazardous Substances Data)
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109539-57-3 Usage
Uses
Used in Pharmaceutical Applications:Leucinostatin K is used as an antibacterial and antifungal agent for its ability to disrupt the cell membrane of target organisms, leading to their death. This makes it a potential candidate for the development of new antimicrobial drugs to combat drug-resistant infections.
Used in Anticancer Applications:
Leucinostatin K is used as an anticancer agent due to its capacity to induce apoptosis in cancer cells. Its potential to modulate oncological signaling pathways and exhibit synergistic effects with conventional chemotherapeutic drugs makes it a promising candidate for cancer therapy.
Used in Enzyme Inhibition:
Leucinostatin K is used as an enzyme inhibitor, with its inhibitory effects on certain enzymes suggesting its potential in the development of new therapeutic agents for various diseases.
Used in Agricultural Applications:
Leucinostatin K is used as a biopesticide for its antibacterial and antifungal properties, which can help protect crops from harmful pathogens and reduce the need for chemical pesticides, thus promoting sustainable agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 109539-57-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,5,3 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.Calculate Digit Verification of CAS Registry Number 109539-57:
(8*1)+(7*0)+(6*9)+(5*5)+(4*3)+(3*9)+(2*5)+(1*7)=143
143 % 10 = 3
So 109539-57-3 is a valid CAS Registry Number.
InChI:InChI=1/C62H111N11O14/c1-19-38(9)23-24-49(77)73-34-40(11)32-47(73)55(82)67-46(31-39(10)30-43(75)33-42(74)20-2)53(80)69-50(51(78)37(7)8)56(83)71-61(15,16)58(85)68-44(28-35(3)4)52(79)66-45(29-36(5)6)54(81)70-62(17,18)59(86)72-60(13,14)57(84)64-26-25-48(76)65-41(12)22-21-27-87-63/h23-24,35-41,43-47,50-51,75,78H,19-22,25-34,63H2,1-18H3,(H,64,84)(H,65,76)(H,66,79)(H,67,82)(H,68,85)(H,69,80)(H,70,81)(H,71,83)(H,72,86)/b24-23+/t38-,39?,40?,41?,43?,44?,45?,46?,47?,50?,51?/m1/s1
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leucinostatin K
