109540-62-7Relevant academic research and scientific papers
Copper(II) triflate catalyzed allylic arylation of allylic alcohols: Direct and selective access to C-allylanilines
Chen, Ke,Chen, Houguang Jeremy,Wong, Jonathan,Yang, Jinglei,Pullarkat, Sumod A.
, p. 3882 - 3888 (2013)
Copper(II) triflate was used as a simple and commercially available catalyst in the direct amination of allylic alcohols with anilines to provide C-allylanilines. A wide range of functional groups were tolerated under the reaction conditions, and the products were obtained regioselectivity without the need of an activator. A detailed mechanistic investigation was undertaken. The efficacy of this protocol was demonstrated in the conversion of the 2-allylanilines into substituted quinolines through an oxidative cycloaddition reaction. All(yl) is good: The direct and selective synthesis of C-allylanilines through Cu(OTf)2-catalyzed (OTf=trifluoromethanesulfonyl) allylic amination involving allylic alcohols and anilines is reported. The reaction can be performed under mild conditions and shows wide functional group tolerance and regioselectivity; the products are obtained in good to high yields. Detailed mechanistic investigations are also discussed. Copyright
Palladacycle-catalyzed tandem allylic amination/allylation protocol for one-pot synthesis of 2-allylanilines from allylic alcohols
Chen, Ke,Li, Yongxin,Pullarkat, Sumod A.,Leung, Pak-Hing
supporting information; experimental part, p. 83 - 87 (2012/04/04)
An efficient methodology involving the predominant formation of C-C bonds is described for the first direct synthesis of 2-allylanilines from allylic alcohols via a one-pot tandem allylic amination/ allylation protocol catalyzed by a palladacycle under mild conditions without the requirement for additional activators.
Alkenylation of anilines with dicyclopentadiene, cyclopentadiene, and piperylene
Gataullin,Kazhanova,Sagitdinov,Galyautdinov,Fatykhov,Spirikhin,Abdrakhmanov
, p. 280 - 285 (2007/10/03)
Alkenylation of anilines with dicyclopentadiene, cyclopentadiene, and piperylene in the presence of mineral acids and Lewis acids was studied.
AMINO-CLAISEN REARRANGEMENT AS A METHOD FOR THE SYNTHESIS OF C-SUBSTITUTED ANILINES
Abdrakhmanov, I. B.,Sharafutdinov, V. M.,Nigmatullin, N. G.,Sagitdinov, I. A.,Tolstikov, G. A.
, p. 1278 - 1283 (2007/10/02)
Various C-alkenylanilines were synthesized by an amino-Claisen rearrangement.The composition of the rearrangement products is affected by the nature of the substituents in the benzene ring and at the nitrogen atom of the initial anilines.
