109545-09-7

Basic information

• Product Name: 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl pyridine-3-carboxylate
• Synonyms: 3-Pyridinecarboxylic acid, 5-(2-(dimethylamino)ethyl)-2,3,4,5-tetrahydro-2-(4-methoxyphenyl)-4-oxo-1,5-benzothiazepin-3-yl ester
• CAS NO: 109545-09-7
• Molecular Formula: C₂₆H₂₇N₃O₄S
• Molecular Weight: 477.5753
• Mol File: 109545-09-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 672.4°C at 760 mmHg
• Flash Point: 360.4°C
• Density: 1.31g/cm³
• Vapor Pressure: 6.12E-18mmHg at 25°C
• Refractive Index: 1.654
• CAS DataBase Reference: 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl pyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl pyridine-3-carboxylate(109545-09-7)
• EPA Substance Registry System: 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl pyridine-3-carboxylate(109545-09-7)

Safety Data

• Hazardous Substances Data: 109545-09-7(Hazardous Substances Data)

Relevant articles and documents

1,5-Benzothiazepines with cardiovascular utility, and pharmaceutical compositions containing them

New 1,5-benzothiazepines of the following general formula STR1 wherein: R1 represents (C1-4)alkyl, (C1-4)alkoxy or a halogen atom; R2 is selected from: benzoyl independently substituted with 1 to 3 (C1-4)alkyl or (C1-4)alkoxy groups, or with halogen atoms; phenylcarbamoyl; phenylcarbamoyl independently substituted with 1 to 3 (C1-4) alkyl or (C1-4) alkoxy groups or with halogen atoms; the groups R5 -CO, in which R5 is the radical deriving from a heterocyclic ring optionally substituted by a (C1-4)alkyl or a (C1-4)alkoxy radical, or by a halogen atom; R3 and R4 independently represent (C1-4)alkyl groups; and salts therewith of pharmaceutically acceptable acids. The compounds of the invention possess cardiovascular utility.