109547-63-9Relevant academic research and scientific papers
The synthesis of some derivatives based on the 4-Benzyl-1H-Pyrazole-3,5- Diamine core
Jedinak, Lukas,Krystof, Vladimir,Cankara, Petr
experimental part, p. 371 - 383 (2011/04/15)
The three-step synthesis of 4-benzyl-1H-pyrazole-3,5-diamines 2 from commercially available aldehydes 3 is given. The Knoevenagel condensation was utilized to assemble the initial carbon framework, resulting in the benzylidenemalononitriles 4 which were d
The Reactions of Benzylmalononitriles with Hydrazine and Hydroxylamine. Synthesis of Pyrazoles, Isoxazoles, and Pyrazolo-pyrimidine Derivatives
Vaquero, Juan J.,Fuentes, Luis,Castillo, Juan C. Del,Perez, Maria I.,Garcia, Jose L.,Soto, Jose L.
, p. 33 - 35 (2007/10/02)
Benzylmalononitriles react with hydrazine or hydroxylamine to give 4-substituted 3,5-diaminopyrazoles or isoxazoles, respectively.Pyrazolopyrimidine derivatives are prepared by reaction of these pyrazoles with some 2,3-disubstituted propenenitriles
