1095532-15-2Relevant academic research and scientific papers
Organocatalytic enantioselective aminosulfenylation of α,β- unsaturated aldehydes
Zhao, Gui-Ling,Rios, Ramon,Vesely, Jan,Eriksson, Lars,Cordova, Armando
supporting information; experimental part, p. 8468 - 8472 (2009/04/18)
(Chemical Equation Presented) Domino theory: A simple, highly enantioselective organocatalytic aminosulfenylation of α,β- unsaturated aldehydes affords orthogonally protected β-amino-α- mercaptoaldehydes in high yields and 93 to >99% ee (see scheme, Bn=benzyl). Notably, the catalytic transformation shows that it is possible to efficiently employ all components of an electrophile, which includes a nucleofuge, in organocatalytic domino reactions of enals.
