1095544-81-2

Basic information

• Product Name: 1-bromo-2-fluoro-4,5-dimethoxybenzene
• Synonyms: 1-bromo-2-fluoro-4,5-dimethoxybenzene
• CAS NO: 1095544-81-2
• Molecular Formula: C₈H₈BrFO₂
• Molecular Weight: 235.0503232
• EINECS: -0
• Mol File: 1095544-81-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 231.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.489±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-bromo-2-fluoro-4,5-dimethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-fluoro-4,5-dimethoxybenzene(1095544-81-2)
• EPA Substance Registry System: 1-bromo-2-fluoro-4,5-dimethoxybenzene(1095544-81-2)

Safety Data

• Hazardous Substances Data: 1095544-81-2(Hazardous Substances Data)

Usage

General Description

1-Bromo-2-fluoro-4,5-dimethoxybenzene is a chemical compound with the molecular formula C8H8BrFO2. It is a member of the aromatic hydrocarbons family and consists of a benzene ring with two methoxy (CH3O) groups and one bromine (Br) and one fluorine (F) atoms attached to it. 1-Bromo-2-fluoro-4,5-dimethoxybenzene is mainly used in organic synthesis, particularly as a building block for the production of pharmaceuticals and agrochemicals. It can also be used as a reagent in various chemical reactions, such as nucleophilic substitution and cross-coupling reactions, due to the presence of reactive bromine and fluorine atoms on the benzene ring. Additionally, it has potential applications in material science and can serve as a starting material for the synthesis of various functionalized aromatic compounds. Overall, 1-Bromo-2-fluoro-4,5-dimethoxybenzene is a versatile chemical with diverse applications in the field of organic chemistry.

Upstream product

• 398-62-9 4-fluoroveratrole 

Downstream Products

• 1095543-33-1 1-(2-fluoro-4,5-dimethoxyphenyl)piperazine 
• 656804-73-8 4-bromo-5-fluorobenzene-1 ,2-diol 

Relevant articles and documents

General Synthetic Approach to Rotenoids via Stereospecific, Group-Selective 1,2-Rearrangement and Dual S N Ar Cyclizations of Aryl Fluorides

A general synthetic approach to rotenoids is described, featuring 1) stereospecific, group-selective 1,2-rearrangements of epoxy alcohols, and 2) S N Ar oxy-cyclizations of aryl fluorides. The common intermediate epoxyketone, en route to (-)-rotenone and (-)-deguelin, was prepared from d -araboascorbic acid in five steps. Also described is the conversion of (-)-deguelin into oxidized congeners, (-)-tephrosin and (+)-12a- epi -tephrosin.

2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists

Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein R is R1, R2, R3, R4 and R5 are H, alkyl or alkoxyalkyl; R6 is H, alkyl, hydroxyalkyl or —CH2F; R7, R8 and R9 are H, alkyl, alkoxy, alkylthio, alkoxyalkyl, halo or —CF3; and Z is optionally substituted aryl, heteroaryl or heteroaryl-alkyl are disclosed. Also disclosed is the use of compounds of formula I in the treatment of central nervous system diseases, in particular Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, and pharmaceutical compositions comprising them.