1095823-62-3Relevant articles and documents
METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND
-
Paragraph 0601-0605, (2020/11/27)
The aim of the present invention is to provide a method capable of producing an optically active pyrimidinamide derivative on an industrial scale. Compound (I) or a salt thereof is subjected to an asymmetric reduction reaction, the obtained compound (II) or a salt thereof is subjected to a deprotection reaction, and the obtained compound (III) or a salt thereof is reacted with compound (VI) or a salt thereof to obtain compound (V) or a salt thereof. wherein each symbol is as defined in the specification.
Heterocyclic Compounds Useful as RAF Kinase Inhibitors
-
Page/Page column 36, (2009/01/24)
The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.