109583-12-2 Usage
Uses
Used in Pharmaceutical Synthesis:
2-Azabicyclo[2.2.2]octane-3-carboxylic acid,(3S)-(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and chiral properties enable the development of enantiomerically pure compounds, which are crucial for the production of effective and safe medications.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Azabicyclo[2.2.2]octane-3-carboxylic acid,(3S)-(9CI) serves as a versatile building block for the creation of a wide range of organic compounds. Its bicyclic structure and functional groups allow for various chemical reactions, facilitating the synthesis of complex molecules with specific properties.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
2-Azabicyclo[2.2.2]octane-3-carboxylic acid,(3S)-(9CI) is utilized as a chiral auxiliary in asymmetric synthesis to control the stereochemistry of the reaction products. This is particularly important in the synthesis of enantiomerically pure compounds, which are often required for biological activity and pharmaceutical applications.
Used in the Chemical Industry:
The unique structure and properties of 2-Azabicyclo[2.2.2]octane-3-carboxylic acid,(3S)-(9CI) make it a valuable compound in the chemical industry. It can be used as a precursor for the synthesis of various specialty chemicals, including chiral ligands, catalysts, and other functional materials.
Check Digit Verification of cas no
The CAS Registry Mumber 109583-12-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,5,8 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 109583-12:
(8*1)+(7*0)+(6*9)+(5*5)+(4*8)+(3*3)+(2*1)+(1*2)=132
132 % 10 = 2
So 109583-12-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H13NO2/c10-8(11)7-5-1-3-6(9-7)4-2-5/h5-7,9H,1-4H2,(H,10,11)
109583-12-2Relevant articles and documents
SATURATED FUSED [1,2-B] PYRIDAZINONE COMPOUNDS
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Page/Page column 85, (2008/12/06)
The invention is directed to saturated fused [1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
Selection of a 2-azabicyclo[2.2.2]octane-based α4β1 integrin antagonist as an inhaled anti-asthmatic agent
Lawson, Edward C.,Santulli, Rosemary J.,Dyatkin, Alexey B.,Ballentine, Scott A.,Abraham, William M.,Rudman, Sandra,Page, Clive P.,de Garavilla, Lawrence,Damiano, Bruce P.,Kinney, William A.,Maryanoff, Bruce E.
, p. 4208 - 4216 (2007/10/03)
The α4β1 integrin, expressed on eosinophils and neutrophils, induces inflammation in the lung by facilitating cellular infiltration and activation. From a number of potent α4β1 antagonists that we evaluated for
Synthesis and Conformational Studies of Zabicipril (S9650-3), a Potent Inhibitor of Angiotensin Converting Enzyme
Vincent, Michel,Pascard, Claudine,Cesario, Michele,Remond, Georges,Bouchet, Jean-Paul,et al.
, p. 7369 - 7372 (2007/10/02)
The synthesis of the title compound 8c is described.This inhibitor of Angiotensin Converting Enzyme (ACE) contains aza-2 bicyclooctane-carboxylic acid, a bulky cyclic amino acid replacing the proline moiety present in most ACE inhibitors described
