1095944-23-2Relevant academic research and scientific papers
Inter-and intra-molecular cyclisation reactions of azoacetates derived from aryl hydrazones of ethyl acetoacetate and acetoacetanilides
O'Halloran, Neil,James, John P.,Downey, Carol A.,O'Malley, Patrick,Duff, Thomas,Bertrand, Samuel
, p. 2681 - 2701 (2011/04/16)
The base induced cyclisations of azoacetates to azetidinones were investigated. In addition to the isolation of the desired products, it was found that 2-iminopyrrolidine-5-one derivatives as well as N-acyl hydrazides could be isolated when metal cyanides were employed as base. These entities were further modified to form pyrrolidine-2,5-diones and diazetidinones respectively. The Japan Institute of Heterocyclic Chemistry.
