109605-06-3Relevant academic research and scientific papers
Ruthenium-catalyzed synthesis of substituted 2-hydroxymorpholines and substituted morpholines
Su,LeBas,Kopecky,Knifton
, p. 871 - 874 (2007/10/02)
The reaction of primary amines with peroxides afforded substituted hydroxymorpholines which were then converted to substituted morpholines via dihydrooxazines as intermediates. The reaction appears to proceed through a ruthenium-catalyzed dehydrogenation-cyclization process.
Process for preparing hydroxymorpholines
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, (2008/06/13)
This invention relates to the reaction of aliphatic epoxides and primary amines to form hydroxymorpholines or morpholines by a process comprising reacting said epoxide and primary amine in the presence of a ruthenium-containing compound plus a tertiary ph
