1096162-18-3Relevant academic research and scientific papers
Synthesis of α-helix mimetics with four side-chains
Restorp, Per,Rebek Jr., Julius
, p. 5909 - 5911 (2008)
The synthesis of a heterocyclic piperazine-based scaffold that mimics the i, i + 4, i + 8, i + 11 side-chain projections of an α-helix is described. The synthesis is designed to be modular to allow the targeting of a range of protein-protein interactions involving α-helices.
