1096357-17-3Relevant academic research and scientific papers
Synthesis of benzimidazoles from 1,1-dibromoethenes
Shen, Wang,Kohn, Todd,Fu, Zice,Jiao, XianYun,Lai, Sujen,Schmitt, Michael
, p. 7284 - 7286 (2008)
A mild and efficient method for the preparation of substituted benzimidazoles from 1,1-dibromoethenes and o-diaminobenzenes is described. The reaction employs DABCO as the base and NMP as the solvent. A variety of substitutions on both 2-aryl-1,1-dibromoethenes and o-diaminobenzenes are tolerated. This new procedure is carried out under mildly basic conditions, which may provide a complementary route to the existing preparations of benzimidazoles.
