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109642-01-5

EBAB is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 109642-01-5 Structure

  • Basic information

    1. Product Name: EBAB
    2. Synonyms:
    3. CAS NO:109642-01-5
    4. Molecular Formula:
    5. Molecular Weight: 296.375
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 109642-01-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: EBAB(CAS DataBase Reference)
    10. NIST Chemistry Reference: EBAB(109642-01-5)
    11. EPA Substance Registry System: EBAB(109642-01-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 109642-01-5(Hazardous Substances Data)

109642-01-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 109642-01-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,6,4 and 2 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 109642-01:
(8*1)+(7*0)+(6*9)+(5*6)+(4*4)+(3*2)+(2*0)+(1*1)=115
115 % 10 = 5
So 109642-01-5 is a valid CAS Registry Number.

109642-01-5Downstream Products

109642-01-5Relevant articles and documents

1,2-Ethane bis-1-amino-4-benzamidine is active against several brain insult and seizure challenges through anti-NMDA mechanisms targeting the 3H-TCP binding site and antioxidant action

Vamecq, Joseph,Maurois, Pierre,Pages, Nicole,Bac, Pierre,Stables, James P.,Gressens, Pierre,Stanicki, Dimitri,Eynde, Jean Jacques Vanden

experimental part, p. 3101 - 3110 (2010/09/03)

Five bis-benzamidines were screened towards murine magnesium deficiency-dependent audiogenic seizures, unravelling two compounds with efficacious doses 50 (ED50) less than 10 mg/kg. They were also screened against maximal electroshock and subcutaneous pentylenetetrazole- induced seizures, and explored for superoxide -scavenging activity. 1,2-Ethane bis-1-amino-4-benzamidine (EBAB) was selected and evaluated in 6 Hz seizure test (ED50= 49 mg/kg) and at 4 μg/kg in focal cerebral ibotenate poisoning in pups (sizes of both white and grey matter wounds were halved). EBAB was further tested on NMDA-induced seizures in mice (ED50=6 mg/kg) and on 3H-TC -binding to a rodent cerebral preparation (IC50=1.4 μM). Taken as a whole, present data emphasise the suitability of bis-benzamidines as templates for designing brain protective compounds.

Bisbenzamidine derivatives for use as antioxidant

-

, (2009/12/05)

The invention is directed to the use of bisbenzamidine compounds of Formula (I) as antioxidant and as neuroprotective agents, wherein R1, R2, R3, R4 and L have the meaning defined in the claims.

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