109649-84-5Relevant academic research and scientific papers
3-aryl coumarin derivative as well as preparation method and application thereof
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Paragraph 0137-0140, (2021/07/17)
The invention discloses a 3-aryl coumarin derivative as well as a preparation method and application thereof. The preparation method comprises the following steps of: carrying out tandem condensation-lactonization reaction on substituted phenylacetic acid
Hydroxyl substitutional effect on selective synthesis of CIS, trans stilbenes and 3-arylcoumarins through perkin condensation
Xiao, Chun-Fen,Zou, Yong,Du, Jian-Li,Sun, Hong-Yi,Liu, Xian-Ke
experimental part, p. 1243 - 1258 (2012/04/04)
The substitutional effect in the selective synthesis of cis, trans stilbenes and 3-arylcoumarins has been described. The regio- and geometrical selectivity for synthesis of stilbene derivatives under the Perkin strategy strongly depends on the presence or absence of hydroxyl group as well as their positions in the phenyl ring. As a result, practical synthetic strategies were established for preparing various natural stilbenes including combretastatin A-4, pterostilbene, and resveratrol with satisfactory yields (49.2-63.7%). Copyright Taylor & Francis Group, LLC.
