109686-21-7Relevant academic research and scientific papers
AN EFFICIENT RESOLUTION OF 3-TRIFLUOROMETHYL-γ-BUTYROLACTONE AND ITS CONVERSION TO 5,5,5-TRIFLUOROLEUCINOL
Taguchi, Takeo,Kawara, Akihiro,Watanabe, Shotaro,Oki, Yukihiro,Fukushima, Hisashi,et al.
, p. 5117 - 5120 (1986)
3-Trifluoromethyl-γ-butyrolactone(2) was effectively resolved via its diastereomeric amide(3). 5,5,5-Trifluoroleucinol hydrochloride(8) were prepared in enantiomerically pure form and the absolute configurations were determined by CD spectra of dibenzoyl
