1096945-39-9

Upstream product

• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 1191279-68-1 C₂₀H₁₆N₄O₃ 
• 1191279-69-2 2-(4-cyanophenylamino)-6-(2,4,6-trimethylphenoxy)-3-nitropyridine 
• 1191279-71-6 N₂-(4'-cyanophenyl)-6-(2'',6''-dimethyl-4''-iodo)phenoxy-3-nitropyridin-2-amine 
• 1191279-70-5 2-(4-cyanophenylamino)-6-(2,6-dimethyl-4-hydroxymethylphenoxy)-3-nitropyridine 
• 1191279-72-7 2-(4-cyanophenylamino)-6-(2,6-dimethyl-4-cyanophenoxy)-3-nitropyridine 
• 1229013-89-1 2-(4-cyanophenylamino)-6-(methylamino)-3-nitropyridine 
• 1221441-36-6 N²-(4'-cyanophenyl)amino-6-(2'',6''-dibromo-4''-formyl)phenoxy-3-nitropyridine 
• 1221441-38-8 N²-(4'-cyanophenyl)amino-6-(2'',6''-difluoro)phenoxy-3-nitropyridine 
• 1221441-35-5 N²-(4'-cyanophenyl)amino-6-(2'',4'',6''-tribromo)phenoxy-3-nitropyridine 

Relevant academic research and scientific papers

META-DIARYLANILINE OR META-DIARYLPYRIDINAMINE COMPOUND, PREPARATION METHOD AND MEDICAL USES THEREOF

Meta-diarylaniline or meta-diarylpyridinamine compounds, methods for preparing the same and uses thereof in manufacture of a medicament. The compounds according to the present application have strong inhibitory activity (at nM level) against wild-type and various drug-resistant HIV viral strains, exhibit good druggability, and can be easily synthesized.

2-(4-SUBSTITUTED PHENYLAMINO) POLYSUBSTITUTED PYRIDINE COMPOUNDS AS INHIBITORS OF NON-NUCLEOSIDE HIV REVERSE TRANSCRIPTASE, PREPARATION METHODS AND USES THEREOF

The invention relates to 2-(4-Substituted phenylamino) polysubstituted pyridine compounds as inhibitors of non-nucleoside HIV reverse transcriptase, preparation methods and uses thereof. Specifically, the invention relates to compounds of formula I or the

THE 2-(4-SUBSTITUTED PHENYLAMINO) POLYSUBSTITUTED PYRIDINE COMPOUNDS AS THE INHIBITORS OF NON-NUCLEOSIDE HIV REVERSE TRANSCRIPTASE, PRAPARATION METHODS AND USES THEREOF

The invention relates to 2-(4-Substituted phenylamino) polysubstituted pyridine compounds as inhibitors of non-nucleoside HIV reverse transcriptase, preparation methods and uses thereof. Specifically, the invention relates to compounds of formula I or the

NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME

The present invention relates to a novel 2,6-substituted-3-nitropyridine derivative compound, a method for preparing the same, and a pharmaceutical composition including the same for prevention and treatment of osteoporosis. The 2,6-substituted-3-nitropyr

NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME

The present invention relates to a novel 2,6-substituted-3-nitropyridine derivative compound, a method for preparing the same, and a pharmaceutical composition including the same for prevention and treatment of osteoporosis. The 2,6-substituted-3-nitropyr

Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

On the basis of the structures and activities of our previously identified non-nucleoside reverse transcriptase inhibitors (NNRTIs), we designed and synthesized two sets of derivatives, diarylpyridines (A) and diarylanilines (B), and tested their anti-HIV

Discovery of diarylpyridine derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Two series (4 and 5) of diarylpyridine derivatives were designed, synthesized, and evaluated for anti-HIV-1 activity. The most promising compound, 5e, inhibited HIV-1 IIIB, NL4-3, and RTMDR1 with low nanomolar EC50 values and selectivity indexe