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4-amino-N-[6-chloro-2-(pyrrolidin-1-yl)pyrimidin-4-yl]benzenesulfonamide is a complex organic compound with the molecular formula C15H18ClN5O2S. It is a derivative of benzenesulfonamide, featuring a pyrimidine ring with a chloro substituent at the 6-position and a pyrrolidin-1-yl group at the 2-position. The compound also contains an amino group at the 4-position and a sulfonamide group. This chemical is known for its potential applications in pharmaceutical research, particularly as a precursor or intermediate in the synthesis of various biologically active molecules. Its structure and properties make it a candidate for further exploration in drug development, given its ability to form hydrogen bonds and its potential to interact with specific biological targets.

1097-17-2

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1097-17-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1097-17-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1097-17:
(6*1)+(5*0)+(4*9)+(3*7)+(2*1)+(1*7)=72
72 % 10 = 2
So 1097-17-2 is a valid CAS Registry Number.

1097-17-2Downstream Products

1097-17-2Relevant academic research and scientific papers

5-HT6 receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides

Boes, Michael,Sleight, Andrew J.,Godel, Thierry,Martin, James R.,Riemer, Claus,Stadler, Heinz

, p. 165 - 178 (2007/10/03)

RO-04-6790 (6a) has been identified in a random screen for 5-HT6 receptor antagonists. In a medicinal chemistry optimisation program a series of analogs comprising N-heteroaryl- and N-arylbenzenesulfonamides have been synthesised and investigated for their binding affinity. Compounds with a log D profile indicative of brain penetration have been subjected to in vivo testing for reversal of a scopolamine-induced retention deficit in a passive avoidance paradigm.

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