1097010-36-0Relevant academic research and scientific papers
Synthesis, in vitro and in silico anticancer activity of new 4-methylbenzamide derivatives containing 2,6-substituted purines as potential protein kinases inhibitors
Bozhok, Tatyana,Faryna, Aliaksandr,Kalinichenko, Elena,Panibrat, Alesya
, (2021/11/30)
A novel class of potential protein kinase inhibitors 7–16 was synthesized in high yields using various substituted purines. The most promising compounds, 7 and 10, exhibited inhibitory activity against seven cancer cell lines. The IC50 values f
Synthesis and biological evaluation of 1,2,4-triazole and 1,3,4-thiadiazole derivatives as potential cytotoxic agents
Shi, Yao-Jie,Song, Xue-Jiao,Li, Xiao,Ye, Ting-Hong,Xiong, Ying,Yu, Luo-Ting
, p. 1099 - 1104 (2014/01/06)
A series of new 3-amino-5-sulfanyl-1,2,4-triazole and 2-amino-5-sulfanyl-1, 3,4-thiadiazole derivatives have been synthesized and their cytotoxicities were evaluated on a panel of human cancer cell lines (BxPC-3, H1975, SKOV-3, A875, HCT116, etc.). The be
