1097188-65-2Relevant academic research and scientific papers
Synthesis and biological evaluation of a chitobiose-based peptide VV-glycanase inhibitor library
Witte, Martin D.,Horst, Danielle,Wiertz, Emmanuel J. H. J.,Van Der Marel, Gijsbert A.,Overkleeft, Herman S.
supporting information; experimental part, p. 605 - 616 (2009/07/18)
Peptide N-glycanase (PNGase), the enzyme responsible for the deglycosylation of N-linked glycoproteins, has an active site related to that of cysteine proteases. Chitiobiose was equipped with electrophilic traps often used in cysteine protease inhibitors,
