1097200-74-2Relevant academic research and scientific papers
Enol phosphinates and phosphonates: Practical electrophiles for cross-coupling strategies
Steel, Patrick G.,Woods, Tom M.
experimental part, p. 3897 - 3904 (2010/03/24)
Enol phosphinates and phosphonates can be readily prepared from simple lactams in high yields and are both stable and storable. Both these substrates can be employed successfully in homogeneous Suzuki-Miyaura and Stille cross-couplings protocols. Additionally, the phosphonate group can be immobilised on a phenol-on-polystyrene resin and utilised in a simple diversity linker strategy in which the coupled product is cleaved from the resin under Suzuki-Miyaura cross-coupling conditions. Georg Thieme Verlag Stuttgart.
Phosphinates as new electrophilic partners for cross-coupling reactions
Guo, Jun,Harling, John D.,Steel, Patrick G.,Woods, Tom M.
supporting information; experimental part, p. 4053 - 4058 (2009/06/28)
The use of enol phosphinates as electrophiles for cross-coupling reactions has been explored. Both boronic acids (Suzuki-Miyaura reaction) and stannanes (Stille reaction) couple efficiently with lactam derived phosphinates. The 2008 Royal Society of Chemi
