109741-38-0

Usage

Uses

Used in Pharmaceutical Industry:
Murraol is used as a potential medicinal compound for its antimicrobial and anti-inflammatory properties, which can contribute to the development of new treatments and therapies.
Used in Aromatherapy:
Murraol is used as an essential oil for its pleasant aroma, which can provide relaxation and stress relief benefits in aromatherapy practices.
Used in Traditional Indigenous Australian Medicine:
Murraol is used as a healing agent in traditional Indigenous Australian medicine, leveraging its supposed medicinal properties for various health applications.
Used in Fragrance Industry:
Murraol is used as a fragrance ingredient for its eucalyptus and mint-like scent, adding a refreshing and invigorating aroma to various products such as perfumes, soaps, and candles.

Upstream product

• 484-12-8 osthole 
• 5673-37-0 7-methoxy-8-(2',3'-dihydroxy-3'-methylbutyl)coumarin 
• 65763-01-1 7-methoxy-8-iodo-2H-chromen-2-one 
• 115-18-4 2-methyl-3-buten-2-ol 
• 65763-04-4 8-(3-hydroxy-3-methylbut-1-yn-1-yl)-7-methoxy-2H-chromen-2-one 
• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 121994-13-6 peroxymurraol 

Downstream Products

• 114032-24-5 8-Naphthoherniarin 

Related news

Synthesis of the natural coumarins, Murraol (cas 109741-38-0) (CM-c2), trans-dehydroosthol and swietenocoumarin G07/22/2019

The coumarin CM-c2, from Cnidium monnieri, 7-methoxy-8-(3-hydroxy-3-methylbut-1-enyl) coumarin, has been synthesized by palladium acetate-catalysed condensation of 7-methoxy-8-iodocoumarin with 2-methylbut-3-en-2-ol. Its stereochemistry follows from its conversion to trans-dehydroosthol. The ide...detailed

Relevant academic research and scientific papers

SYNTHESIS OF THE NATURAL COUMARINS, MURRAOL (CM-c2), TRANS-DEHYDROOSTHOL AND SWIETENOCOUMARIN G

The coumarin CM-c2 from Cnidium monnieri, 7-methoxy-8-(3-hydroxy-3-methylbut-1-enyl)coumarin, has been synthesized by palladium acetate-catalysed condensation of 7-methoxy-8-iodocoumarin with 2-methylbut-3-en-2-ol.Its stereochemistry follows from its conversion to trans-dehydroosthol.The identity of CM-c2 and murraol has been established.Swietenocoumarin G has been prepared similarly from bergaptol. - Keywords: Cnidium monnieri; Umbelliferae; fruit; coumarin syntheses; CM-c2; murraol; trans-dehydroosthol; swietenocoumarin G.Keywords: Cnidium monnieri; Umbelliferae; fruit; coumarin synthese; CM-c2; murraol; trans-dehydroosthol; swietenocoumarin G.

Half-Sandwich Ruthenium Carbene Complexes Link trans-Hydrogenation and gem-Hydrogenation of Internal Alkynes

The hydrogenation of internal alkynes with [Cp?Ru]-based catalysts is distinguished by an unorthodox stereochemical course in that E-alkenes are formed by trans-delivery of the two H atoms of H2. A combined experimental and computational study now provides a comprehensive mechanistic picture: a metallacyclopropene (??2-vinyl complex) is primarily formed, which either evolves into the E-alkene via a concerted process or reacts to give a half-sandwich ruthenium carbene; in this case, one of the C atoms of the starting alkyne is converted into a methylene group. This transformation represents a formal gem-hydrogenation of a ?€-bond, which has hardly any precedent. The barriers for trans-hydrogenation and gem-hydrogenation are similar: whereas DFT predicts a preference for trans-hydrogenation, CCSD(T) finds gem-hydrogenation slightly more facile. The carbene, once formed, will bind a second H2 molecule and evolve to the desired E-alkene, a positional alkene isomer or the corresponding alkane; this associative pathway explains why double bond isomerization and over-reduction compete with trans-hydrogenation. The computed scenario concurs with para-hydrogen-induced polarization transfer (PHIP) NMR data, which confirm direct trans-delivery of H2, the formation of carbene intermediates by gem-hydrogenation, and their evolution into product and side products alike. Propargylic aOR (R = H, Me) groups exert a strong directing and stabilizing effect, such that several carbene intermediates could be isolated and characterized by X-ray diffraction. The gathered information spurred significant preparative advances: specifically, highly selective trans-hydrogenations of propargylic alcohols are reported, which are compatible with many other reducible functional groups. Moreover, the ability to generate metal carbenes by gem-hydrogenation paved the way for noncanonical hydrogenative cyclopropanations, ring expansions, and cycloadditions.

Cnidimonins A-C, Three Types of Hybrid Dimer from Cnidium monnieri: Structural Elucidation and Semisynthesis

Three pairs of racemic dimers, (±)-cnidimonins A-C (1-3), were isolated from the fruits of Cnidium monnieri. They represent novel hybrid-dimerization patterns of coumarin skeleton with structurally diverse units (flavonol, benzofuran, and chromone) via an

Natural Product Chemistry, 118. - Synthesis of the Coumarins 6- and 8-Naphthoherniarin, Dehydrogeijerin, and Murraol

The Pd/Cu-catalysed reaction of 6-bromo-7-methoxycoumarin (1) with 2-methyl-3-butyn-2-ol yields 1,2-dehydrosuberenol (2).By Lindlar reduction, water elimination, Diels-Alder reaction with 2-methoxy-p-benzoquinone (6), and dehydrogenation with 6-naphthoherniarin (9), a novel coumarin from Ruta graveolens is synthesized.Dehydrogeijerin (8) is available by Schuster-Meyer rearrangement of 2.By Heck vinylation 8-iodo-7-methoxycoumarin (11) is transferred into murraol (12).By water elimination from 12, Diels-Alder reaction with 6 and aromatisation 8-naphthoherniarin (14) is available.