109746-54-5Relevant academic research and scientific papers
Synthesis and Characteristics of Fluorinated Benzofurans
Kucklaender, Uwe,Herweg-Wahl, Ute,Poll, Wolfgang,Rickerich, Lutz
, p. 1841 - 1846 (2007/10/02)
Dihydrobenzofurans 4a-c and g-j were synthesized from 2-acetyl-1,4-benzoquinone (1) and β-diketones 2a-c and g-j and dehydrated to benzofurans 5a-i.The structure of 5d was examined by X-ray analysis.Reaction of quinone 9 and diketone 2g yielded directly fluorinated benzofurans 11a and 12b.The abnormal 1H-NMR spectra of benzofurans 5d, f and 11a are discussed.Formation of ketone hydrates 12a, b and 13 was detected.
Addition of β-Dicarbonyl Compounds to 2-Acetyl-p-benzoquinone
Kucklaender, Uwe,Herweg-Wahl, Ute,Massa, Werner,Baum, Gerhard
, p. 1791 - 1796 (2007/10/02)
The structure of adducts from 2-acetyl-p-benzoquinone (1) and acetoacetates 2a,b is corrected to dihydrobenzofuran derivatives 4a,b.The product from 1 and hexafluoroacetylacetone 5 is examined spectroscopically and by X-ray structure analysis, its structure is cleared up as cycloadduct 6.In solution fast rearrangement of 6 to dihydrobenzofuran 13 is observed.Reaction of 13 with acetyl chloride yields the monoacetate 12, treatment with aqueous acid is followed by cleavage to 14.In acetic acid tetralone derivative 16 is formed, which can be aromatized with acetic anhydride to naphthalene 17 and oxidized to naphthoquinone 18.
