1097637-57-4Relevant articles and documents
Organocatalytic approach to (s)-1-arylpropan-2-ols: Enantioselective synthesis of the key intermediate of antiepileptic agent (-)-talampanel
Sawant, Rajiv T.,Waghmode, Suresh B.
experimental part, p. 2269 - 2277 (2010/09/11)
An efficient organocatalytic route for the preparation of enantioselective synthesis of (S)-1-arylpropan-2-ols derivatives, including the key intermediate of antiepileptic agent (-)-talampanel is described. The key steps involved are L-proline-catalyzed a
First asymmetric total synthesis of novel and cytotoxic 2′-R-hydroxylanneaquinol
Suresh,Rajesh,Jon Paul Selvam,Venkateswarlu
body text, p. 7358 - 7360 (2009/05/07)
A novel cytotoxic alkylated hydroquinone 2′-R-hydroxylanneaquinol (1), isolated from the organic extract of the plant Lannea welwitschii, has been synthesized for the first time using commercially available 4-methoxyphenol. The key step of this process involves the kinetic resolution of epoxide 6 using Jacobsen's reaction conditions.