109768-67-4

Usage

Uses

Used in Pharmaceutical Development:
(4H-Benzo[d][1,3]thiazin-2-yl)-p-tolyl-amine is used as a potential pharmaceutical drug for its ability to modulate certain biological targets and pathways. Its application in this field is driven by the need for new therapeutic agents that can address various diseases and conditions.
Used in Disease Treatment Research:
In the field of medical research, (4H-Benzo[d][1,3]thiazin-2-yl)-p-tolyl-amine is utilized for investigating its potential role in the treatment of a range of diseases and conditions. The exploration of its therapeutic potential is based on its chemical structure and the pharmacological properties of benzo[d]thiazine compounds.
Note: The specific applications and industries for (4H-Benzo[d][1,3]thiazin-2-yl)-p-tolyl-amine are not detailed in the provided materials. The uses listed above are inferred based on the general properties of benzo[d]thiazine compounds and the compound's potential in pharmaceutical applications. Further research would be required to identify specific applications and industries where (4H-Benzo[d][1,3]thiazin-2-yl)-p-tolyl-amine could be utilized.

InChI:InChI=1/C15H14N2S/c1-11-6-8-13(9-7-11)16-15-17-14-5-3-2-4-12(14)10-18-15/h2-9H,10H2,1H3,(H,16,17)

Upstream product

• 5344-90-1 2-Aminobenzyl alcohol 
• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 109768-45-8 2-isothiocyanatobenzylpyridinium bromide 
• 108288-40-0 2-(bromomethyl)phenyl isothiocyanate 
• 109768-48-1 1-[2-(3-p-Tolyl-thioureido)-benzyl]-pyridinium; bromide 
• 106-49-0 p-toluidine 
• 109768-58-3 C₂₀H₁₉N₃S 

Relevant academic research and scientific papers

P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds

A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. P(NMe2)3 revealed the maximum efficacies under the aerobic reaction conditions and a spectrum of bis-nucleophiles, and isothiocyanates were tolerated well to serve the access of manifold immense molecules. (Figure presented.).

Reagent-Controlled Divergent Synthesis of 2-Amino-1,3-Benzoxazines and 2-Amino-1,3-Benzothiazines

A reagent-controlled chemoselective process has been devised for the synthesis of 4H-1,3-benzoxazines and related biologically important heterocycles in high yields under mild conditions. These scaffolds could be efficiently constructed using two different chemoselective reactions that rely on the choice of reagents and reaction conditions. The treatment of various 2-amino-arylalkyl alcohols with isothiocyanates afforded thiourea intermediates, which were reacted in situ with molecular iodine in the presence of triethylamine to give 2-amino-4H-1,3-benzoxazines, whereas the corresponding 2-amino-4H-1,3-benzothiazines were obtained by the reaction of thiourea intermediates in the presence of T3P (a mild cyclodehydrating agent) and triethylamine as the base. The described protocol represents the first example for the synthesis of 4H-1,3-benzoxazines via the dehydrosulfurization method using molecular iodine as the reagent.

2-ISOTHIOCYANATOBENZYLPYRIDINIUM BROMIDE - AN INTERMEDIATE FOR THE SYNTHESIS OF 2-ARYLAMINO-4H-BENZOTHIAZINES

2-Bromomethylphenyl isothiocyanate reacts with pyridine to yield 2-isothiocyanatobenzylpyridinium bromide, which afforded N-aryl-N'-(2-benzylpyridinium)thiourea bromides.Deprotonization of the latter with aqueous NaOH gave N-aryl-N'-(2-benzylpyridinium) t