1097725-72-8

Basic information

• Product Name: 3-methyl-2-N-(p-toluenesulfonyl)aminoimidazo[4,5-b]pyridine
• Synonyms: 3-methyl-2-N-(p-toluenesulfonyl)aminoimidazo[4,5-b]pyridine
• CAS NO: 1097725-72-8
• Molecular Weight: 302.357
• Mol File: 1097725-72-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-2-N-(p-toluenesulfonyl)aminoimidazo[4,5-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-2-N-(p-toluenesulfonyl)aminoimidazo[4,5-b]pyridine(1097725-72-8)
• EPA Substance Registry System: 3-methyl-2-N-(p-toluenesulfonyl)aminoimidazo[4,5-b]pyridine(1097725-72-8)

Safety Data

• Hazardous Substances Data: 1097725-72-8(Hazardous Substances Data)

Upstream product

• 1886-67-5 N-tosyldichloromethanimine 
• 5028-20-6 3-amino-2-methylaminopyridine 

Downstream Products

• 30458-69-6 3-methyl-3H-imidazo[4,5-b]pyridin-2-amine 

Relevant articles and documents

Synthesis and mutagenic potency of structural isomers of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

(Chemical Equation Presented) Synthesis of 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP), three structural isomers, and two desphenyl PhIP congeners has been carried out. Mutagenic potency was evaluated using S. typhimurium strain TA98 in the Ames test. Mutagenic potency increased in relation to structural features in these heterocyclic amines that allow extended resonance between the phenyl and imidazo[4,5-b]pyridine N2-amino substituents. By contrast, PhIP isomers, whose substitution disallows involvement of the phenyl group in their ammoimidazo resonance hybrids, and desphenyl congeners were from 86- to 234-fold less mutagenic than PhIP.