1097862-75-3

Upstream product

• 288-47-1 1,3-thiazole 
• 455-13-0 4-Iodobenzotrifluoride 
• 402-43-7 p-trifluoromethylphenyl bromide 

Downstream Products

• 1401316-10-6 2-(4-methoxyphenyl)-4-phenyl-5-(4-trifluoromethylphenyl)thiazole 
• 1401316-11-7 2-(4-methoxyphenyl)-5-(4-trifluoromethylphenyl)thiazole 
• 1398309-52-8 6,6'-difluoro-2,2'-bibenzo[d]thiazole 
• 1398308-53-6 6-fluoro-2-(5-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzo[d]thiazole 
• 1398308-42-3 6-methoxy-2-(5-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzo[d]thiazole 
• 145673-31-0 6,6'-dimethoxy-2,2'-bibenzo[d]thiazole 
• 1388625-51-1 2-(5-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzothiazole 
• 1388625-53-3 2-(1-methyl-1H-imidazol-2-yl)-5-(4-(trifluoromethyl)phenyl)thiazole 
• 1373612-09-9 2-butylsulfanyl-5-(4-trifluoromethylphenyl)thiazole 

Relevant academic research and scientific papers

Nickel Catalysis Enables Oxidative C(sp2)–H/C(sp2)–H Cross-Coupling Reactions between Two Heteroarenes

Nickel can be used to promote oxidative C(sp2)?H/C(sp2)?H cross-coupling between two heteroarenes. The reaction scope can be extended to aromatic carboxamides as the coupling partner. The reaction exhibits high functional-group compatibility and broad substrate scope. The silver oxidant can be recycled to reduce costs and waste, which is very useful for practical applications.

Programmed synthesis of arylthiazoles through sequential C-H couplings

A programmed synthesis of privileged arylthiazoles via sequential C-H couplings catalyzed by palladium or nickel catalysts has been accomplished. This versatile protocol can supply all possible arylthiazole substitution patterns (2-aryl, 4-aryl, 5-aryl, 2

One-pot sequential direct C-H bond arylation of azoles catalyzed by [Pd(phen)2](PF6)2: Synthetic methods for triarylated azoles

Synthetic methods for triarylated azoles containing three different aryl groups via one-pot sequential multiple C-H bond arylations are described. The one-pot sequential diarylation of C5-monoarylated azoles was achieved by the simple sequential addition of two different aryl iodides with a [Pd(phen) 2]PF6 catalytic system. The one-pot triarylation of N-methylimidazole was achieved by the combination of a previously reported Pd(OAc)2-P(2-furyl)3 system and the present [Pd(phen) 2]PF6 system. In this case, portionwise addition of aryl halide, base and the catalyst in the final step significantly improved the overall yield of the desired triarylated product. These protocols led to triarylated azoles without a loss of efficiency compared to the corresponding previously reported stepwise syntheses via direct C-H bond arylation.