109790-48-9Relevant academic research and scientific papers
Iridium-Catalyzed Asymmetric Hydrogenation of 2H-Chromenes: A Highly Enantioselective Approach to Isoflavan Derivatives
Xia, Jingzhao,Nie, Yu,Yang, Guoqiang,Liu, Yangang,Zhang, Wanbin
, p. 4884 - 4887 (2017)
A highly efficient (aS)-Ir/In-BiphPHOX-catalyzed asymmetric hydrogenation of substituted 2H-chromenes and substituted benzo[e][1,2]oxathiine 2,2-dioxides is described. A series of 2H-chromenes and benzo[e][1,2]oxathiine 2,2-dioxides were hydrogenated to give the target products in high yields (92-99%) with excellent enantioselectivities (up to 99.7% ee) using our catalytic system. This reaction provides a direct and efficient method for the construction of chiral benzo six-membered oxygen-containing compounds.
SYNTHESIS AND ANTI-RHINOVIRUS ACTIVITY OF HALOGEN-SUBSTITUTED ISOFLAVENES AND ISOFLAVANS
Burali, Carla,Desideri, Nicoletta,Stein, M. Luisa,Conti, Cinzia,Orsi, Nicola
, p. 119 - 124 (2007/10/02)
Halogenated 3(2H)-isoflavenes and (+/-)isoflavans were synthesized in order to study their in vitro activity against rhinovirus 1B by comparison with the known anti-viral compound, 4',6-dichloroflavan.The Wittig intramolecular cyclization of halogen subst
