1097939-72-4Relevant academic research and scientific papers
Dehydrative cross-coupling reactions of allylic alcohols with olefins
Gumrukcu, Yasemin,De Bruin, Bas,Reek, Joost N. H.
supporting information, p. 10905 - 10909 (2014/09/17)
The direct dehydrative activation of allylic alcohols and subsequent cross-coupling with alkenes by using palladium catalyst containing a phosphoramidite ligand is described. The activation of the allyl alcohol does not require stoichiometric additives, thus allowing clean, waste-free reactions. The scope is demonstrated by application of the protocol to a series allylic alcohols and vinyl arenes, leading to variety of 1,4-diene products. Based on kinetic studies, a mechanism is proposed that involves a palladium hydride species that activates the allyl alcohol to form the allyl intermediate.
Iron-catalyzed 1,4-addition of α-olefins to dienes
Moreau, Benoit,Wu, Jessica Y.,Ritter, Tobias
supporting information; experimental part, p. 337 - 339 (2009/07/04)
Stereo-and Regiosetective 1,4-Addition A new intermolecular, stereo- and regioselective iron-catalyzed 1,4-addition of α-olefins to 1,3-dlenes using as low as 1 mol % of an iminopyridine-ferrous chloride complex was developed. Importantly, both double bon
