1097967-95-7

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 118-48-9 isatoic anhydride 
• 529-20-4 2-methylphenyl aldehyde 

Relevant academic research and scientific papers

Synthesis of 2,3-dihydroquinazoline-4(1H)-ones

An efficient, inexpensive, and heterogeneous catalyst, [Al(H 2PO4)3], was applied in a three-component, one-pot cyclocondensation reaction of isatoic anhydride with primary amines (or ammonium salts) and aldehydes to afford the corresponding quinazolinone derivatives in excellent yields. Reactions occurred under thermal solvent-free conditions. It was found that this solid acidic catalyst could be easily recovered and reused for at least three cycles without any loss of activity.

Agar: A novel, efficient, and biodegradable catalyst for the one-pot three-component and green synthesis of 2,3-dihydroquinazolin-4(1H)-one, 4H-pyrimidobenzothiazole and 2-aminobenzothiazolomethylnaphthol derivatives

3-(2′-Benzothiazolyl)-2,3-dihydroquinazolin-4(1H)- one, 1-((benzo[d]thiazol-2-ylamino) (aryl)-methyl)naphthalen-2-ol and 4H-pyrimido[2,1-b][1,3]benzothiazoles derivatives were prepared via one-pot three-component reaction of arylaldehydes, 2-aminobenzothiazole and isatoic anhydride or β-naphthol or ethyl/methyl acetoacetate in the presence of agar as a highly efficient homogenous catalyst. The use of a non-toxic and biodegradable catalyst, as well as high yields, short reaction time, simple work-up and green conditions are the most important advantages of this method. Graphical Abstract: [Figure not available: see fulltext.]

New applications of phosphoric acid supported on alumina (H 3PO4-Al2O3) as a reusable heterogeneous catalyst for preparation of 2,3-dihydroquinazoline-4(1H)-ones, 2H-indazolo[2,1-b]phthalazinetriones, and benzo[4,5]imidazo[1,2-a]pyrimidines

An eco-friendly procedure for synthesis of 2,3-dihydroquinazoline-4(1H)- one, 2H-indazolo[2,1-b]phthalazinetrione, and benzo[4,5]imidazo[1,2-a]pyrimidine derivatives by three-component reaction, with phosphoric acid supported on alumina as catalyst, is described. Noticeable features of the method are that it is solvent-free, work-up is easy, yields are excellent, and the catalyst is reusable.

Zr (HSO4)4: An efficient catalyst for the Synthesis of 3-(2'-benzothiazolyl)-2, 3-dihydroquinazolin-4 (1H)-ones

A simple and efficient synthesis of 3- (2'-benzothiazolyl)-2, 3-dihydroquinazolin-4 (1H)-ones has been accomplished by the one-pot condensation of isatoic anhydride, aldehydeand 2-aminobenzothiazole under solvent-free conditionsin the presence of Zr (HSO4)4.

Synthesis of a novel class of 3-(2′-benzothiazolyl)-2,3- dihydroquinazolin-4(1H)-ones under solvent-free and catalyst-free conditions

(Chemical Equation Presented) A solvent- and catalyst-free one-pot three-component condensation reaction approach was developed for the synthesis of a new class of 3-(2′-benzothiazolyl)-2,3-dihydroquinazolin-4(1H)-ones in relatively good yields.