1097967-97-9

Upstream product

• 136-95-8 2-amino-benzthiazole 
• 118-48-9 isatoic anhydride 
• 135-02-4 ortho-anisaldehyde 

Relevant academic research and scientific papers

Zr (HSO4)4: An efficient catalyst for the Synthesis of 3-(2'-benzothiazolyl)-2, 3-dihydroquinazolin-4 (1H)-ones

A simple and efficient synthesis of 3- (2'-benzothiazolyl)-2, 3-dihydroquinazolin-4 (1H)-ones has been accomplished by the one-pot condensation of isatoic anhydride, aldehydeand 2-aminobenzothiazole under solvent-free conditionsin the presence of Zr (HSO4)4.

Synthesis, characterization and catalytic application of tributyl(carboxymethyl)phosphonium bromotrichloroferrate as a new magnetic ionic liquid for the preparation of 2,3-dihydroquinazolin-4(1H)-ones and 4H-pyrimidobenzothiazoles

Abstract: In this paper, tributyl(carboxymethyl)phosphonium bromotrichloroferrate as a new magnetic ionic liquid bearing acetic acid tags was synthesized and characterized by several methods including Fourier transform infrared spectroscopy (FT-IR), energ

One-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones by Fe3O4@SiO2-imid-PMAn nano-catalyst under ultrasonic irradiation and reflux conditions

Abstract: Fe3O4@SiO2-imid-PMAn efficiently catalyzes the condensation reaction of isatoic anhydride, aldehydes, and primary amines or ammonium salts to afford the corresponding 2,3-dihydroquinazolin-4(1H)-one derivatives under ultrasonic irradiation or reflux conditions. This method gives notable advantages such as operational simplicity, excellent yields, short reaction times, and absence of any tedious workup or purification. In addition, the excellent catalytic performance and the easy preparation, thermal stability, and separation of the catalyst make it a good heterogeneous system and a useful alternative to other heterogeneous catalysts. Also, the aforementioned nanocatalyst can be easily recovered by a magnetic field and reused for subsequent reactions for at least six times without noticeable deterioration in catalytic activity and reaction yield. Graphical abstract: [Figure not available: see fulltext.]

Agar: A novel, efficient, and biodegradable catalyst for the one-pot three-component and green synthesis of 2,3-dihydroquinazolin-4(1H)-one, 4H-pyrimidobenzothiazole and 2-aminobenzothiazolomethylnaphthol derivatives

3-(2′-Benzothiazolyl)-2,3-dihydroquinazolin-4(1H)- one, 1-((benzo[d]thiazol-2-ylamino) (aryl)-methyl)naphthalen-2-ol and 4H-pyrimido[2,1-b][1,3]benzothiazoles derivatives were prepared via one-pot three-component reaction of arylaldehydes, 2-aminobenzothiazole and isatoic anhydride or β-naphthol or ethyl/methyl acetoacetate in the presence of agar as a highly efficient homogenous catalyst. The use of a non-toxic and biodegradable catalyst, as well as high yields, short reaction time, simple work-up and green conditions are the most important advantages of this method. Graphical Abstract: [Figure not available: see fulltext.]

New applications of phosphoric acid supported on alumina (H 3PO4-Al2O3) as a reusable heterogeneous catalyst for preparation of 2,3-dihydroquinazoline-4(1H)-ones, 2H-indazolo[2,1-b]phthalazinetriones, and benzo[4,5]imidazo[1,2-a]pyrimidines

An eco-friendly procedure for synthesis of 2,3-dihydroquinazoline-4(1H)- one, 2H-indazolo[2,1-b]phthalazinetrione, and benzo[4,5]imidazo[1,2-a]pyrimidine derivatives by three-component reaction, with phosphoric acid supported on alumina as catalyst, is described. Noticeable features of the method are that it is solvent-free, work-up is easy, yields are excellent, and the catalyst is reusable.

Synthesis of 2,3-dihydroquinazoline-4(1H)-ones

An efficient, inexpensive, and heterogeneous catalyst, [Al(H 2PO4)3], was applied in a three-component, one-pot cyclocondensation reaction of isatoic anhydride with primary amines (or ammonium salts) and aldehydes to afford the corresponding quinazolinone derivatives in excellent yields. Reactions occurred under thermal solvent-free conditions. It was found that this solid acidic catalyst could be easily recovered and reused for at least three cycles without any loss of activity.

Synthesis of a novel class of 3-(2′-benzothiazolyl)-2,3- dihydroquinazolin-4(1H)-ones under solvent-free and catalyst-free conditions

(Chemical Equation Presented) A solvent- and catalyst-free one-pot three-component condensation reaction approach was developed for the synthesis of a new class of 3-(2′-benzothiazolyl)-2,3-dihydroquinazolin-4(1H)-ones in relatively good yields.