1098184-03-2 Usage
Description
(S)-N-Boc-4,4,4,4,4,4-Hexafluorovaline, a derivative of the amino acid valine, is a chemical compound that belongs to the class of fluorinated amino acids. It is characterized by the addition of six fluorine atoms to the carbon chain, which confers unique properties to the compound. These properties include increased metabolic stability, improved bioavailability, and enhanced interactions with biological targets. As a result, (S)-N-Boc-4,4,4,4,4,4-Hexafluorovaline is a promising candidate for various applications in the fields of medicinal chemistry, peptide synthesis, and chemical biology research.
Uses
Used in Pharmaceutical Industry:
(S)-N-Boc-4,4,4,4,4,4-Hexafluorovaline is used as a building block for the development of peptide-based drugs. (S)-N-Boc-4,4,4,4,4,4-Hexafluorovaline's unique properties, such as increased metabolic stability and improved bioavailability, make it an attractive option for the design and synthesis of novel therapeutic agents.
Used in Peptide Synthesis:
In the field of peptide synthesis, (S)-N-Boc-4,4,4,4,4,4-Hexafluorovaline serves as a valuable component for the creation of novel peptide sequences. The fluorine substituents in the compound can lead to altered binding affinities and specific interactions with biological targets, making it a useful tool for the development of new peptides with tailored properties.
Used in Chemical Biology Research:
(S)-N-Boc-4,4,4,4,4,4-Hexafluorovaline is also utilized in chemical biology research, where it can be employed to study the effects of fluorination on protein structure and function. (S)-N-Boc-4,4,4,4,4,4-Hexafluorovaline's unique properties can provide insights into the role of fluorine in biological systems and contribute to the development of new strategies for drug design and target identification.
Check Digit Verification of cas no
The CAS Registry Mumber 1098184-03-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,8,1,8 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1098184-03:
(9*1)+(8*0)+(7*9)+(6*8)+(5*1)+(4*8)+(3*4)+(2*0)+(1*3)=172
172 % 10 = 2
So 1098184-03-2 is a valid CAS Registry Number.
1098184-03-2Relevant articles and documents
Methyl to trifluoromethyl substitution as a strategy to increase the membrane permeability of short peptides
Aikawa, Kohsuke,Morimoto, Jumpei,Okazoe, Takashi,Ono, Takahiro,Sando, Shinsuke
supporting information, p. 9386 - 9389 (2021/11/17)
Here, we investigated the effect of CH3to CF3substitution on the membrane permeability of peptides. We synthesized a series of peptides with CF3groups and corresponding nonfluorinated peptides and measured the membrane per
Substituted hydantoins
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Page/Page column 32, (2008/06/13)
The present invention relates to compounds of the formula methods for the preparation thereof, and methods for their use. The compounds are useful in treating diseases characterized by the hyperactivity of MEK. Accordingly the compounds are useful in the treatment of diseases, such as cancer, cognitive and CNS disorders, and inflammatory/autoimmune diseases.
Long-acting angiotensin II inhibitors containing hexafluorovaline in position 8
Hsieh -h.,Needleman,Marshall
, p. 1097 - 1100 (2007/10/02)
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