109837-89-0Relevant academic research and scientific papers
Thromboxane synthase inhibitors. Synthesis and pharmacological activity of (R)-, (S)-, and (±)-2,2-dimethyl-6-[2-(1H-imidazol-1-yl)-1-[[(4 methoxyphenyl)-methoxy]methyl]ethoxy]hexanoic acids
Manley,Tuffin,Allanson,Buckle,Lad,Lai,Lunt,Porter,Wade
, p. 1812 - 1818 (2007/10/02)
A series of substituted ω-[2-(1H-imidazol-1-yl)ethoxy]alkanoic acid derivatives were synthesized and evaluated for their ability to inhibit thromboxane synthase both in vitro and in vivo. Compound 13 was identified as a potent and selective competitive in
