109849-38-9

Upstream product

• 78004-28-1 6-(benzyloxy)-7-methoxyisoquinoline 
• 201230-82-2 carbon monoxide 

Downstream Products

• 98809-69-9 6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 56633-08-0 6-(benzyloxy)-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Rhodium catalyzed hydrogenation of quinolines and isoquinolines under water-gas shift conditions

Wide variety of quinolines and isoquinolines can be hydrogenated selectively in the nitrogen-containing ring by means of carbon monoxide and water in the presence of catalytic amount of rhodium carbonyl cluster. These reactions provide a useful method for the preparation of 1,2,3,4-tetrahydroquinolines and 1,2,3,4-tetrahydroisoquinolines which are key intermediates for the synthesis of isoquinoline alkaloids and other biologically active nitrogen compounds.

RHODIUM CATALYZED HYDROGENATION OF NITROGEN HETEROAROMATICS UNDER WATER GAS SHIFT CONDITIONS. SELECTIVE SYNTHESIS OF 1,2,3,4-TETRAHYDROQUINOLINES AND N-FORMYL-1,2,3,4-TETRAHYDROISOQUINOLINES

Quinolines and isoquinolines are hydrogenated selectively in the nitrogen-containing ring by means of carbon monoxide and water in the presence of catalytic amount of rhodium carbonyl cluster.