109853-15-8Relevant articles and documents
Synthesis of New 1,2,4-Triazolines and 1,3,4-Thiadiazolines from Bithioureas
Ernst, Steffen,Richter, Christian,Hobert, Annette,Mariam, Getachew G.,Schulze, Klaus
, p. 275 - 282 (2007/10/02)
2,4-Disubstituted thiosemicarbazides 1 react with acyl isothiocyanates to give bithioureas 2, which by the action of sodium ethanolate cyclize to 1,2,4-triazoline-3-thiones 3 and 5, respectively.Treatment of 2 with methyl iodide yields 1,3,4-thiadiazoline