109876-18-8

Upstream product

• 106-37-6 1.4-dibromobenzene 
• 83-56-7 1,5-dihydroxynaphthalene 
• 10075-63-5 1,5-dimethoxynaphthalene 
• 181042-92-2 1-(4-Bromo-α-hydroxybenzyl)-4,8-dimethoxynaphthalene 
• 181042-90-0 1-(4-Bromobenzoyl)-4,8-dimethoxynaphthalene 
• 69833-11-0 4,8-dimethoxy-1-naphthaldehyde 
• 126402-55-9 Sodium; 4-(4,8-dimethoxy-naphthalen-1-ylmethyl)-benzenesulfinate 
• 109876-22-4 1-(4-Bromobenzyl)-4,8-dimethoxynaphthalene 

Downstream Products

• 181042-95-5 (S)-2-[4-(4,8-Dimethoxy-naphthalen-1-ylmethyl)-benzenesulfonylamino]-pentanedioic acid di-tert-butyl ester 
• 126402-46-8 4-(4,8-Dimethoxy-naphthalen-1-ylmethyl)-N-phenethyl-benzenesulfonamide 

Relevant academic research and scientific papers

Synthesis and evaluation of photolabile sulfonamides as potential reagents for rapid photorelease of neuroactive amines

The synthesis is described of photolabile sulfonamide derivatives of amino acids, most of which incorporate a monophosphate ester to promote water solubility. Points of particular synthetic interest include observations on the reduction of diaryl ketones

A NEW AMINO PROTECTING GROUP READILY REMOVABLE WITH NEAR ULTRAVIOLET LIGHT AS AN APPLICATION OF ELECTRON-TRANSFER PHOTOCHEMISTRY

As an extension of organic photochemistry via intermolecular electron-transfer in donor-acceptor pair systems between electron-rich aromatic compounds and electron-deficient tosyl groups, we report here a new protecting group for the amino-function, 4-(4,8-dimethoxy-naphthylmethyl)benzenesulfonyl (DNMBS) group, which is readily removed, via an intramolecular electron-transfer followed by hydrolysis, with a high quantum efficiency on irradiation with light longer than 300 nm.

An Improved Synthesis of Arylsulfonyl Chlorides from Aryl Halides

Arylsulfonyl chlorides 8 are prepared from aryl bromides 5 via lithium arylsulfinates 7 in excellent yields.