109901-79-3

Upstream product

• 53008-65-4 methyl 2,3,4-tri-O-benzyl-D-glucopyranoside 
• 109681-21-2 2β-chloro-3β-hydroxy-4,7,8,9-tetra-O-acetyl-N-acetylneuraminic acid methyl ester 
• 109681-08-5 methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2-bromo-2,5-dideoxy-D-erythro-α-L-gluco-non-2-ulopyranosonate 
• 109681-20-1 methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,3-anhydro-5-deoxy-β-D-erythro-L-gluco-non-2-ulopyranosonate 
• 73960-72-2 methyl-2,3-didehydro-4,7,8,9-tetra-O-acetyl-N-acetylneuraminate 

Downstream Products

• 90124-30-4 methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside 
• 111192-14-4 methyl 2,3,4-tri-O-benzyl-6-O--β-D-erythro-L-gluco-2-nonulopyranosyl)onate>-α-D-glucopyranoside 

Relevant academic research and scientific papers

AN EFFECTIVE SYNTHESIS OF α-GLYCOSIDES OF N-ACETYLNEURAMINIC ACID DERIVATIVES BY USE OF 2-DEOXY-2β-HALO-3β-HYDROXY-4,7,8,9-TETRA-O-ACETYL-N-ACETYLNEURAMINIC ACID METHYL ESTER

Condensation of the acetyl protected 2-deoxy-2β-halo-3β-hydroxy-N-acetylneuraminic acid methyl ester with various acceptors such as properly protected glucose, galactose, and lactose derivatives in the presence of silver triflate gave the NeuAc α-glycosid

Glycosylation of 4,7,8,9-Tetra-O-acetyl-2-deoxy-2β,3β-epoxy-N-acetylneuraminic Acid Methyl Ester

Reaction of the 2β,3β-epoxyneuraminic acid derivative prepared from 2,3-dehydroneuraminic acid derivative with primary or secondary alcohol gave the corresponding glycoside(s) or ortho ester.

AN EFFECTIVE SYNTHESIS OF α-GLYCOSIDES OF N-ACETYLNEURAMINIC ACID BY USE OF 2β-HALO-3β-HYDROXY-4,7,8,9-TETRA-O-ACETYL-N-ACETYLNEURAMINIC ACID METHYL ESTER

Glycosylations of 2β-chloro- and 2β-bromo-3β-hydroxy-N-acetylneuraminic acid derivatives with various acceptors such as 6-unprotected glucose, 3-unprotected galactose, and 3'-unprotected lactose derivatives (1.0 equiv) were carried out in the presence of