109979-71-7Relevant academic research and scientific papers
Facile access to methoxylated 2-phenylnaphthalenes and epoxydibenzocyclooctenes
Maurin, Cédric,Bailly, Fabrice,Cotelle, Philippe
, p. 7054 - 7058 (2007/10/03)
Methoxylated phenylethanals were treated with concentrated hydrochloric acid in 1,4-dioxane to give methoxylated 2-phenylnaphthalenes or 1,2,9,10-tetrahydro-1,9-epoxydibenzo[a,e]cyclooctenes. Yields in 2-phenylnaphthalenes were quite good and 1,2,9,10-tetrahydro-1,9-epoxydibenzo[a, e]cyclooctenes could be easily isolated. 2-Phenylnaphthalenes were obtained by a tandem aldol condensation-intramolecular Friedel-Crafts cyclisation and 1,2,9,10-tetrahydro-1,9-epoxydibenzo[a,e]cyclooctenes by a O-condensation followed by a double intramolecular Friedel-Crafts alkylation.
