109987-49-7

Upstream product

• 1291066-68-6 (1S)-1-((4R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-((2S)-oxiran-2-yl)-ethyl tert-butyldimethyl-silyl ether 
• 1336937-59-7 (1S,3R)-4-(benzyloxy)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-butane-1,3-diol 
• 1336937-62-2 (1S,3R)-4-(benzyloxy)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-butane-1,3-diyl diacetate 
• 1336937-68-8 (2S,4R)-5-(benzyloxy)pentane-1,2,4-triol 

Downstream Products

• 109987-50-0 (E)-(2R,4R)-1-Benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-oct-6-ene-2,4-diol 
• 1336937-73-5 (2R,4R)-1-(benzyloxy)nonadec-6-yne-2,4-diol 
• 1336937-76-8 (4R,6R)-4-(benzyloxymethyl)-2,2-dimethyl-6-(pentadec-2-ynyl)-1,3-dioxane 
• 109987-51-1 [(E)-4-((4R,6R)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-but-2-enyloxy]-tert-butyl-dimethyl-silane 

Relevant academic research and scientific papers

Synthesis and configuration of the nonadecenetriol isolated from seeds of Persea americana

In an effort to establish the relative as well as absolute configuration of the trypanocidally active natural nonadec-6-en-1,2,4-triol isolated from Persea americana, the (2S,4R), (2S,4S), and (2R,4R) isomers were synthesized. The stereogenic centers take

Total synthesis of C19 lipid diols containing a 2,5-disubstituted-3-oxygenated tetrahydrofuran

The total synthesis of the C19 lipid diols 5 and 6, the enantiomers of the anthelmintic marine natural products 1 and 3, is described. Key steps in the divergent syntheses include a syn selective epoxidation of a homoallylic alcohol, a one-pot alkoxypalladation-carbonylation-lactonisation reaction sequence and a DMEAD promoted Mitsunobu inversion.