110011-82-0

Basic information

• Product Name: (1S)-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine
• CAS NO: 110011-82-0
• Molecular Formula: C₁₇H₁₉NO
• Molecular Weight: 253.3389
• Mol File: 110011-82-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 369.5°C at 760 mmHg
• Flash Point: 109°C
• Density: 1.064g/cm³
• Vapor Pressure: 1.18E-05mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: (1S)-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine(110011-82-0)
• EPA Substance Registry System: (1S)-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine(110011-82-0)

Safety Data

• Hazardous Substances Data: 110011-82-0(Hazardous Substances Data)

Usage

General Description

"(1S)-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine" is a chemical compound that belongs to the class of benzoxazocine derivatives. It has a molecular formula of C17H19NO and a molecular weight of 253.34 g/mol. (1S)-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine is a psychoactive drug that acts as a selective G protein-biased agonist at the κ-opioid receptor, which means it has potential pharmaceutical applications as an analgesic and treatment for addiction. It is also known for its potential for abuse and dependence, making it a controlled substance in many countries. The compound's stereochemistry, with the (1S) designation, indicates the specific orientation of its chiral center, which can have significant effects on its biological activity and pharmacological properties.

Upstream product

• 84940-28-3 1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine-5-carbonitrile 
• 85-52-9 2-Benzoylbenzoic acid 
• 22103-85-1 2-benzoylbenzoyl chloride 
• 24833-47-4 2-benzoyl-N-(2-hydroxyethyl)-N-methylbenzamide 
• 60725-36-2 2-[{2-[hydroxyl(phenyl)methyl]benzyl}(methyl)amino]ethanol 
• 23327-57-3 nefopam hydrochloride 
• 17494-19-8 2,3-dihydro-9b-phenyloxazolo<2,3-a>isoindol-5(9bH)-one 
• 18409-76-2 2-(1-phenyl-2,3-dihydro-1H-isoindol-2-yl)ethanol 

Downstream Products

• 129356-73-6 (+/-)-nefopam methiodide 
• 91463-82-0 (R)-5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine 
• 23327-57-3 nefopam hydrochloride 
• 13831-42-0 2-[(2-benzylbenzyl)(methyl)amino]ethanol 
• 60725-36-2 2-[{2-[hydroxyl(phenyl)methyl]benzyl}(methyl)amino]ethanol 
• 119-61-9 benzophenone 
• 66091-32-5 (1R,5S)/(1S,5R)-nefopam N-oxide 
• 66091-32-5 (1R,5R)/(1S,5S)-nefopam N-oxide 
• 129356-74-7 Nefopam trideuteriomethioiodide 
• 129356-74-7 Nefopam trideuteriomethioiodide 
• 865-50-9 iodomethane-d3 

Relevant articles and documents

MALODOR COUNTERACTING COMPOSITION AND AGENT AND THE USE THEREOF

The present invention relates to a malodor counteracting composition. In particular the invention relates to a malodor counteracting composition comprising nefopam, or a polymorph, a hydrate or a solvate thereof. The invention also relates to the use of said composition and attenuator or suppressor, for attenuating or suppressing malodors, in particular earthy, musty and/or moldy malodors.

A PROCESS FOR THE RESOLUTION OF NEFOPAM

A process for increasing the optical purity of a mixture of enantiomers of nefopam uses a substantially single enantiomer of a O,O-diaroyltartaric acid as a resolving agent, via a bisnefopam salt of the acid. This salt is new.

Benzoxazocines: a new chemical class of centrally acting skeletal muscle relaxants.

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