110026-90-9

Upstream product

• 93604-54-7 3-methyl-4-(phenylthio)-2,5-dihydrothiophene 1,1-dioxide 
• 74-88-4 methyl iodide 

Downstream Products

• 129111-77-9 2,3-Dimethyl-2-geranyl-4-phenylthio-2,5-dihydrothiophene 1,1-Dioxide 
• 129111-78-0 (6E)-3,4,7,11-Tetramethyl-2-phenylthio-1,3,6,10-dodecatetraene 
• 129111-79-1 (3E,6E)-3,4,7,11-Tetramethyl-2-(phenylsulfinyl)-1,3,6,10-dodecatetraene 
• 129111-81-5 (3Z,6E)-3,4,7,11-Tetramethyl-2-(phenylsulfinyl)-1,3,6,10-dodecatetraene 

Relevant academic research and scientific papers

Regio- and Stereoselective Synthesis of Substituted 2-(Phenylthio)-1,3-butadienes

Sulfur-substituted 1,3-butadienes are useful reagents in organic synthesis.We now report two general methods for the regio- and stereoselective synthesis of substituted 2-(phenylthio)-1,3-butadienes 4 and 5. 3-(Phenythio)-3-sulfolenes 2 can be specifically alkylated at C5 under basic conditions.Extrusion of sulfur dioxide by lithium aluminum hydride then gives the dienes 4.On the other hand 2-substituted 3-sulfolenes 11 can be converted to the 3-phenylthio derivatives 9, which upon heating give the dienes 5.