ALPHA-ACTININ is a rod-shaped antiparallel dimer with two elongated subunits, belonging to the spectrin superfamily and localized in actin structures. It has an N-terminal actin-binding domain with tandem calponin homology domains, a central tandem 3-helix motifs, and EF-hand motifs at the C-terminus.
11003-00-2
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Basic information
- Product Name: ALPHA-ACTININ
- Synonyms: ALPHA-ACTININ;A-actinin from chicken gizzard;α-actinin from chicken gizzard
- CAS NO:11003-00-2
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: Actin/Actin-binding ProteinsProteins and Derivatives;Actinin;Cell Signaling and Neuroscience;Cytoskeleton and Extracellular Matrix;Structural Proteins;proteins
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /ammonium sulfate suspension
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: ALPHA-ACTININ(CAS DataBase Reference)
- NIST Chemistry Reference: ALPHA-ACTININ(11003-00-2)
- EPA Substance Registry System: ALPHA-ACTININ(11003-00-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 11003-00-2(Hazardous Substances Data)
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11003-00-2 Usage
Uses
Used in Biochemical Research:ALPHA-ACTININ is used as an antigen to coat plates for the capture of anti-actinin antibody using enzyme-linked immunosorbent assay (ELISA) from tumor cell line clones.
Used in In Vitro Motility Experiments:
ALPHA-ACTININ is used to test its effect on actin filament movement.
Used in Force Measurement Studies:
ALPHA-ACTININ is used to coat cantilevers for strengthening fluorescently labeled actin filaments in force measurement studies.
Biochem/physiol Actions
α-Actinin binds actin and has the ability to crosslink actin cytoskeleton. It also plays a key role in the structural maintenance of the Z-disk of striated muscle.Check Digit Verification of cas no
The CAS Registry Mumber 11003-00-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,0 and 3 respectively; the second part has 2 digits, 0 and 0 respectively.Calculate Digit Verification of CAS Registry Number 11003-00:
(7*1)+(6*1)+(5*0)+(4*0)+(3*3)+(2*0)+(1*0)=22
22 % 10 = 2
So 11003-00-2 is a valid CAS Registry Number.
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11003-00-2Downstream Products
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ALPHA-ACTININ
