1100308-49-3Relevant articles and documents
Biomimetic carbene-catalyzed oxidations of aldehydes using TEMPO
Guin, Joyram,De Sarkar, Suman,Grimme, Stefan,Studer, Armido
supporting information; experimental part, p. 8727 - 8730 (2009/05/15)
(Chemical Equation Presented) Transition-metal-free organocatalytic oxidations of various aldehydes proceed with the TEMPO radical as a mild organic oxidant; the resulting TEMPO esters are formed in moderate to excellent yields (see scheme). N-Heterocyclic carbenes (NHCs) are efficient catalysts and activate aldehydes for electron-transfer reactions. The TEMPO esters are readily hydrolyzed and the nitroxide can be regenerated by aerobic oxidation.