110045-53-9Relevant academic research and scientific papers
Antimalarial Activity of 2-(Substituted amino)-4,6-bis(trichloromethyl)-1,3,5-triazines and N-(Chlorophenyl)-N'-guanidines
Werbel, Leslie M.,Elslager, Edward F.,Hess, Carolyn,Hutt, Marland P.
, p. 1943 - 1948 (2007/10/02)
A series of 2-amino>-4,6-bis(trichloromethyl)-1,3,5-triazines (III) and N-(4-chlorophenyl)-N'-amino>-6-(trichloromethyl)-1,3,5-triazin-2-yl>guanidines (IV) were prepared from 2,4,6-tris(trichloromethyl)-1,3,5-triazine and 2-chloro-4,6-bis(trichloromethyl)-1,3,5-triazine.Compounds of type III showed modest antimalarial activity while XIa with the camoquin side chain was more potent.Analogues of type IV broadly exhibited modest antimalarial activity.
