1100696-89-6

Basic information

• Product Name: C₁₆H₁₂BrF₃O₂
• CAS NO: 1100696-89-6
• Molecular Weight: 373.169
• Mol File: 1100696-89-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₂BrF₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₂BrF₃O₂(1100696-89-6)
• EPA Substance Registry System: C₁₆H₁₂BrF₃O₂(1100696-89-6)

Safety Data

• Hazardous Substances Data: 1100696-89-6(Hazardous Substances Data)

Upstream product

• 454-91-1 (S)-1-(3-trifluoromethylphenyl)ethanol 
• 82892-00-0 N-(4-bromobenzoyl)imidazole 

Relevant articles and documents

Enantioselective, ketoreductase-based entry into pharmaceutical building blocks: Ethanol as tunable nicotinamide reductant

(Chemical Equation Presented) The use of NADH- and NADPH-dependent ketoreductases to access enantioenriched pharmaceutical building blocks is reported. Seven structurally diverse synthons are obtained, including those for atomoxetine (KRED 132), talampanel (RSt-ADH and CPADH), Dolastatin (KRED 132), and fluoxetine (KRED 108/132). Ethanol may be used as stoichiometric reductant, regenerating both nicotinamide cofactors, particularly under four-electron redox conditions. Its favorable thermodynamic and economic profile, coupled with its advantageous dual cosolvent role, suggests a new application for biomass-derived ethanol.