1100744-70-4Relevant academic research and scientific papers
Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
Mohamed Gomha, Sobhi,Sami Shawali, Ahmad,Osman Abdelhamid, Abdou
, p. 865 - 879 (2014/12/10)
A new, less expensive, solvent-free procedure was developed for the synthesis of some new derivatives of various fused heterocyclic ring systems, namely azolopyridazine, azolotriazine, azinotriazine, thienopyridine, and pyrazolopyridine. The structures of the products prepared were established by their spectral data and elemental analyses. Eight compounds were evaluated for their in vitro antimicrobial activity. Some of the tested compounds exhibited moderate to significant antibacterial and antifungal activities.
Synthesis of novel pyrazolo[3,4-d]pyridazine, pyrido[1,2-a]benzimidazole, pyrimido[1,2-a]benzimidazole and triazolo[4,3-a]pyrimidine derivatives
Shaaban, Mohamed R.,Eldebss, Taha M. A.,Darweesh, Ahmed F.,Farag, Ahmad M.
experimental part, p. 1739 - 1744 (2009/05/31)
(Chemical Equation Presented) 4-Acetyl-5-methyl-1-phenyl-1H-pyrazole reacts with dimethylformamide dimethylacetal (DMF-DMA) to afford the corresponding (E)1-(5-methyl-1-phenyl-1H-pyrazol-4-yl)-3-(N,N-dimethylamino)-2-propen-1-one. The latter product under
