1100748-66-0 Usage
Spiro compound
Yes
Explanation
A spiro compound is a type of organic compound that contains two rings connected by a single atom. In this case, the diazaspiro ring system is connected to the undecane chain.
Explanation
The diazaspiro ring system is a part of the molecule, consisting of two nitrogen atoms and a spiro connection.
Explanation
1,9-Diazaspiro[5.5]undecane, 9-(phenylmethyl)is used as a building block in organic synthesis, which is the study of the formation and manipulation of carbon-containing compounds.
Explanation
The compound is also used as a building block in pharmaceutical research, which involves the development of new drugs and medicines.
Explanation
The compound can be used to synthesize various bioactive compounds, which are molecules that have an effect on biological systems.
Explanation
The compound can be used to synthesize pharmaceutical agents, which are drugs or medications used in the treatment or prevention of diseases.
Explanation
Due to its unique structural features, the compound may have potential applications in medicinal chemistry, which involves the design and development of new drugs.
Explanation
The compound may also have potential applications in drug discovery, which is the process of finding new drugs and therapies to treat diseases.
Diazaspiro ring system
Yes
Phenylmethyl substituent
9th position
Organic synthesis
Building block
Pharmaceutical research
Building block
Bioactive compounds
Potential synthesis
Pharmaceutical agents
Potential synthesis
Medicinal chemistry
Potential applications
Drug discovery
Potential applications
Check Digit Verification of cas no
The CAS Registry Mumber 1100748-66-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,0,7,4 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1100748-66:
(9*1)+(8*1)+(7*0)+(6*0)+(5*7)+(4*4)+(3*8)+(2*6)+(1*6)=110
110 % 10 = 0
So 1100748-66-0 is a valid CAS Registry Number.
1100748-66-0Relevant articles and documents
Synthesis of four novel natural product inspired scaffolds for drug discovery
Jenkins, Ian D.,Lacrampe, Fabienne,Ripper, Justin,Alcaraz, Lilian,Van Le, Phuc,Nikolakopoulos, George,De Leone, Priscila Almeida,White, Rodney H.,Quinn, Ronald J.
experimental part, p. 1304 - 1313 (2009/07/04)
Inspired by the novel spiro structures of a number of bioactive natural products such as the histrionicotoxins, a series of novel spiro scaffolds have been designed and robust syntheses developed. The scaffolds are ready-to-use building blocks and can be easily prepared on a 5-20 g scale. They contain two amino groups (one Boc-protected) and have been designed for ease of conversion to a lead generation library, using either amide formation or reductive amination procedures. The synthesis of the 1,9-diazaspiro[5.5]undecane and 3,7-diazaspiro[5.6]dodecane ring systems was achieved using RCM as the key step. A simple workup procedure is reported for the removal of highly colored ruthenium residues. The synthesis of the 1,8-diazaspiro[4.5]decane scaffold has been achieved using a bromine-mediated 5-endo cyclization of the corresponding 4-aminobutene intermediate under acidic conditions. This is the first example of this type of cyclization to be reported. A novel mechanism involving a bromine transfer reaction from an initially formed bromonium ion to a neighboring nitrogen atom is suggested as the reason for the failure of this type of reaction under "normal" bromination conditions. An unusual rearrangement of a 1-acyl-1,9-diazaspiro[5.5]undecane to the corresponding 9-acyl-1,9-diazaspiro[5.5]undecane is reported.
